Long term effects of lead poisoning include:

The long-term effects of lead poisoning are particularly concerning, especially related to cognitive and behavioral outcomes. Lead exposure, especially in children, can interfere with the development of the nervous system, leading to various learning disabilities. This is due to lead's ability to affect neurodevelopment, where it can disrupt synaptic development and neurotransmitter function, ultimately impairing cognitive capabilities.

Learning disabilities can manifest in various ways, such as difficulties in reading, attention problems, and challenges in problem-solving. Evidence from numerous studies supports the link between elevated blood lead levels and declines in academic performance.

In contrast, the other options listed do not typically relate to lead poisoning. Severe acne is generally linked to hormonal changes or certain medications, rather than heavy metal exposure. Loss of large motor skills is not a recognized direct consequence of lead poisoning; while motor skills can be affected, the more significant attention is placed on fine motor skills and cognitive impairments. Lastly, adult diabetes is influenced by metabolic factors, genetics, and lifestyle rather than lead exposure. Therefore, learning disabilities most accurately reflect the long-term impacts of lead poisoning.